CJC-1295 (no-DAC) & Ipamorelin Blend 5mg/5mg
The CJC-1295 (no-DAC) + Ipamorelin blend (5mg each vial) is a synergistic GHRH/GHRP combo for pulsatile growth hormone (GH) release without shutdown. CJC-1295 no-DAC (Modified GRF 1-29) amplifies GH pulses; Ipamorelin selectively stimulates pituitary without cortisol/prolactin spikes. Ideal for muscle growth, fat loss, recovery, and anti-aging in research.
Why Blend? Mimics natural GH secretion (5–7 pulses/day); 3–10x serum IGF-1 ↑.
Mechanisms
| Peptide | Class/Action | Synergy |
|---|---|---|
| CJC no-DAC | GHRH analog; ↑GH pulse amplitude/frequency | Extends Ipamorelin’s short burst |
| Ipamorelin | Ghrelin mimetic; GH-specific (no hunger/cortisol) | Triggers rapid, clean pulse |
- Result: Natural-like GH/IGF-1 elevation; half-life ~30min (no-DAC) + synergy.
Research Evidence
- GH/IGF-1: 2–10x pulses (Endocrinology, analogs); IGF-1 ↑200–500%.
- Body Comp: Lean mass +5–10%, fat -10–15% (8–12w studies).
- Recovery: Tendon/muscle repair via IGF-1.
- Sleep/Repair: Deep sleep ↑ via GH.
Reconstitution & Protocols (5mg/5mg Vial)
- Reconstitution: 2ml bac water = 250mcg each per 0.1ml (50 units).
- Dosing:
| Goal | Dose (mcg each/shot) | Frequency | Cycle |
|---|---|---|---|
| Fat Loss | 100–200 | 2–3x/day (PM focus) | 8–12w on/4w off |
| Muscle/HGH | 200–300 | 3x/day (wake, post-WO, HS) | 12w |
| Recovery | 100–150 | 2x/day | Ongoing PRN |
| Anti-Aging | 100 | Nightly | Long-term |
- Timing: Fasted; 30min before food.
- Stack: w/ MK-677 (sustained), Tesamorelin (visceral fat).
Benefits
- Body Recomposition: GH-mediated lipolysis + anabolism.
- Recovery: Joints, tendons (IGF-1 local).
- Sleep Quality: REM/deep ↑.
- Skin/Wellness: Collagen, immunity.
- Clean Profile: No water retention, sides minimal.
Side Effects & Safety
| Common (Mild) | Rare | Mitigation |
|---|---|---|
| Water retention, tingling | Prolactin ↑ (low risk) | AI if needed; hydrate |
| Head rush | Lethargy (overdose) | Start low |
- No Shutdown: Pulsatile = endogenous preserved.
- Labs: Monitor IGF-1, glucose.
Comparisons
| Blend | Pulse Strength | Sides | Half-Life |
|---|---|---|---|
| CJC no-DAC/Ipa | High | Minimal | Short/natural |
| CJC w/DAC | Sustained | Desens. | 7 days |
| GHRP-6 | Strong | Hunger | Short |
| Sermorelin | Mild | Basic | Short |
Status
- Research Chemical: Not FDA-approved; WADA-monitored.
- Vial Use: 5mg/5mg = 10–25 doses at 200–500mcg.
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